Dr Haqq

Dr. Andrea Haqq

Dr. Andrea Haqq at the University of Alberta in Edmonton
SUPPORT RENOWNED PWS RESEARCH IN OUR OWN BACKYARD

Alberta’s own Dr. Andrea Haqq and colleagues in the Department of Pediatrics at the University of Alberta are currently conducting three research projects associated with Prader-Willi Syndrome. . Please consider participating in one or more of Dr. Haqq’s research projects listed below.

University of Alberta Information sheet about Dr Haqq

 

PWS RESEARCH STUDIES

Study 1: Gut Microbiome in Infants and Children with PWS (funded by Prader-Willi Syndrome Association USA)

The human gut contains bacteria (called gut microbes) that play an important role in food digestion. Changes in gut microbes are associated with obesity, but the role of gut microbes in the regulation of body weight in children with PWS is not fully understood. In our study, we will compare the gut microbe composition of children with PWS to individuals of similar age, gender and body weight who do not have PWS. 

We are recruiting children with and without PWS ages birth to 17 years. Reimbursement for parking at the University of Alberta, Edmonton, Alberta, for the study visit will be provided. For participants living outside the Edmonton region, we will mail the stool collection kit and study questionnaires. 

What will participants be asked to do in this study?

Participants will be asked to:

  • have their weight, height and waist measured
  • answer questions about their appetite
  • provide a stool sample (a container for collection will be provided before the study visit) 
  • complete a 3-day food record

For more information about the study please contact Shima Afhami at afhami@ualberta.ca 

Study 2: Impact of Diet on Metabolism and Appetite in Children with PWS (funded by Stollery Children’s Hospital Foundation through Women & Children’s Health Research Institute)

Body weight is determined by the balance between the amount of calories eaten and the amount of calories used during the day. In our study, we will examine if the type of meal eaten has an effect on the amount of calories are used and on appetite in children with PWS compared to children who do not have PWS. 

We are recruiting children with and without PWS ages 10 to 17 years. Reimbursement for travel to the University of Alberta campus from within Alberta is available. 

What will participants be asked to do in this study?

Children will come to the University of Alberta for three study visits (3 to 7 hours each visit). During the study visits participants will be asked to:

  • have their weight, height, waist and body composition measured
  • stay in a room for up to 6 hours to have their metabolic rate measured 
  • eat a specific diet the day before and during the study visits
  • have a catheter inserted into their arm for five blood samples during each study visit

For more information about the study please contact Maha Alsaif at alsaif@ualberta.ca 

Study 3: GLWL-01 in the treatment of PWS (funded by GLWL Research Inc.)

A study is being conducted to evaluate the safety and effectiveness of GLWL-01 in treating the feeling of hunger in individuals with PWS. You can participate if you have a confirmed diagnosis of PWS, are between 16 and 65 years of age, have a Body mass index (BMI) of 27 to 60 kg/m2, had a weight stable over the preceding 3 months prior to study, and have difficulty controlling hunger related behaviours.

What will participants be asked to do?
1. Before starting the study, participants will undergo a screening process to see if they are eligible to take part in this study.  The screening period may last up to 28 days.  

2. Total involvement in the study: 22 weeks (154 days)

3. Eight visits to the University of Alberta, Edmonton, AB, Canada. During these visits, blood and urine samples will be collected.

4. Participants will also receive 3 phone calls from the site. 

For more information about the study, please contact Kristie at the Alberta Diabetes Institute Clinical Research Unit:  780-492-1098, adicru@ualberta.ca 


Raylene participated in the first of two sessions of a now non recruiting research study Dr. Haqq was conducting at the U of A. These were taken the last day they were there but they at least show the machine. In the actual study Raylene was wearing a bathing suit and bathing cap. The lady standing beside Raylene is Sarah, who was conducting the study.